Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia

Endemic Pneumocystis Carinii Pneumonia

The entity of interstitial plasma cell pneumonia due to Pneumocystis carinii has received increasing attention during the past 10 years. Extensive studies and reviews concerning this problem, its epidemiology and pathogenesis (Ahvenainen, 1957; Bachmann, 1954; Cahalane, 1962; Jirovec, 1 960a and b; Muller and Vietor, 1957), its clinical course and picture (Berdnikoff, 1959; Dvorak and Jirovec, ...

[Pneumocystis carinii pneumonia].

A study is carried out in 8 infants with a diagnosis of Pneumocystis carinii pneumonia which was established through the study of histologic lung sections, and a microscopic study of protozoas. The following are some of the factors predisposing to this disease: prematurity, significant denutrition, primary immunodeficiencies, extended use of antibiotics, malignancies, and immunosuppressive trea...

Diagnosis of Pneumocystis carinii Pneumonia

A diagnosis of PneumocysHs carinii pneumonia was made in seven patients by the technique of transbronchoscopic lung biopsy. In this technique, flexible forceps are inserted through a rigid broncbosrrope. No false wgathre re& were obtained, that is, no other cases of pneumocysHs pneumonia were discovered by any additional technique, including autopsy, among a group of 525 patients with difiuse p...

Histologically atypical Pneumocystis carinii pneumonia.

BACKGROUND Infection with Pneumocystis carinii typically results in a pneumonia which histologically is seen to consist of an eosinophilic foamy alveolar exudate associated with a mild plasma cell interstitial infiltrate. Special stains show that cysts of P carinii lie within the alveolar exudate. Atypical histological appearances may occasionally be seen, including a granulomatous pneumonia an...

Pneumocystis carinii pneumonia and reticuloses.